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STEAP3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520406

Catalog No. PIPA520406


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Description

Description

A suggested positive control is rat liver tissue lysate. PA5-20406 can be used with blocking peptide PEP-0523.

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
Specifications

Specifications

STEAP3
Polyclonal
Unconjugated
STEAP3
Liquid
STEAP3
A 15 amino acid peptide from near the amino terminus of human STEAP3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q658P3, Q8CI59, Q5RKL5
STMP3, TSAP6, dudlin-2; 1010001D01Rik; dudlin 2; dudulin 2; dudulin-2; hTSAP6; hpHyde; metalloreductase STEAP3; pHyde; six transmembrane prostate protein 3; six-transmembrane epithelial antigen of prostate 3; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
170824, 55240, 68428
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