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STEAP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520407

Catalog No. PIPA520407


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Description

Description

A suggested positive control is rat liver tissue lysate. PA5-20407 can be used with blocking peptide PEP-0524.

The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
Specifications

Specifications

STEAP4
Polyclonal
Unconjugated
STEAP4
Liquid
STEAP4
A 14 amino acid peptide from near the center of human STEAP4.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q687X5, Q923B6, Q4V8K1
STAMP2, TIARP, TNFAIP9; metalloreductase STEAP4; six transmembrane prostate protein 2; six-transmembrane epithelial antigen of prostate 4; sixTransMembrane protein of prostate 2; tumor necrosis factor, alpha-induced protein 9; tumor necrosis-alpha-induced adipose-related protein
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
117167, 499991, 79689
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