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STIM1 Rabbit anti-Bovine, Canine, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA146217

Catalog No. PA146217


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Description

Description

The target sequence has 93% sequence homology with porcine and 79% sequence homology with xenopus. Suggested positive control: antigen standard for STIM1 (transient overexpression lysate), HeLa whole cell lysate.

Stromal interaction molecule 1 plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores. It acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, it translocates from the endoplasmic recticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit.
Specifications

Specifications

STIM1
Polyclonal
Unconjugated
STIM1
Liquid
STIM1
Synthetic peptide made to a C-terminal region with residues 600-685 of the human protein.[UniprotNo.Q13586]
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Canine, Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 30% glycerol and 0.1% sodium azide
Q58CP9, Q13586, P70302, P84903
D11S4896E, GOK
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
20866, 361618, 534816, 608643, 6786
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