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STIP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527835

Catalog No. PIPA527835


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Description

Description

PA5-27835 targets STIP1 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27835 immunogen is recombit fragment corresponding to a region within amino acids 231 and 542 of Human STIP1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
Specifications

Specifications

STIP1
Polyclonal
Unconjugated
STIP1
Liquid
STIP1
Recombit fragment corresponding to a region within amino acids 231 and 542 of Human STIP1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.89 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
P31948
HOP, IEF-SSP-3521, P60, STI1, STI1L, Hsp70/Hsp90-organizing protein, NY-REN-11 antigen, hsc70/Hsp90-organizing protein, renal carcinoma antigen NY-REN-11, transformation-sensitive protein IEF SSP 3521
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10963
Documents
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