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STK16 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514078

Catalog No. PIPA514078

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Specifications

Specifications

STK16
Polyclonal
PBS with 0.09% sodium azide
O75716, O88697
Serine/threonine protein kinase 16, Protein kinase PKL12, Myristoylated and palmitoylated serine-threonine kinase, MPSK, TGF-beta stimulated factor 1, TSF-1, hPSK
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
20872, 8576
Immunohistochemistry, Western Blot
Unconjugated
STK16
Liquid
STK16
KLH conjugated synthetic peptide between 257-286 amino acids from the C-terminal region of human STK16
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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