STK33 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523081
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.Serine Threonine Kinase 33 is normally expressed in embryonic and germ-line cells, which ultimately differentiate into testis, lung, heart, brain and spinal cord. It is critical in both spermatogenesis and organ ontogenesis, and is thus a critical developmental protein. However, in many maligt tissues, STK33 is abnormally expressed, and its appearance in these tissues usually indicates an increase in the cancer cell viability. In cancer cells, STK33 suppresses mitochondrial apoptosis, which precludes normal processes to identify and eliminate cancerous cells.
|A synthetic peptide made to an internal region of the human Stk33 (within residues 1-150).|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 30% glycerol and 0.05% sodium azide|
|serine/threonine-protein kinase 33|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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