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SUMO2/SUMO3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA511319

Catalog No. PIPA511319


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Description

Description

This antibody is predicted to react with bovine, chicken, hamster, porcine, non-human primate, rat and Xenopus and zebrafish based on sequence homology.

SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
Specifications

Specifications

SUMO2/SUMO3
Polyclonal
Unconjugated
SUMO2
Liquid
SUMO2, SUMO3
KLH conjugated synthetic peptide between 49-81 amino acids from the C-terminal region of human SUMO2/3
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human, Mouse
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
P55854, P61956, P61957, Q9Z172
Sumo3, SUMO2, SMT3A, SMT3H1, SUMO-3, Smt3B, SMT3 homolog 1, SMT3 suppressor of mif two 3 homolog 1, SUMO-2, small ubiquitin-related modifier 3, ubiquitin-like protein SMT3A, ubiquitin-like protein SMT3B
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
170930, 20610, 6612, 6613
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