anti-Superoxide Dismutase 1 Polyclonal, Thermo Scientific™

Superoxide Dismutase 1 Polyclonal Ab PA1-18276 from Thermo Scientific™ detects Superoxide Dismutase 1 in Hu samples, and is validated for IHC (Paraffin, Frozen) and WB

Manufacturer: Invitrogen PA118275

 View more versions of this product

Catalog No. 01-670-528

  Check Availability
Add to Cart

    Specifications

    Antigen Superoxide Dismutase 1
    Applications Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Mouse,Rat
    Format Serum
    Formulation 100μL unpurified antibody in whole serum and no preservative
    Gene Accession No. P07632, P08228
    Gene Alias SOD1, ALS, ALS1, Cu/Zn superoxide dismutase, Homodimer, Indophenoloxidase A, IPOA
    Gene Symbols SOD1
    Host Species Rabbit
    Immunogen Synthetic peptide corresponding to residues A(24) S G E P V V L S G Q I T(36) of mouse superoxide dismutase (SOD1).
    Isotype IgG
    Quantity 100μL
    Species Reactivity Mouse, Rat
    Storage Requirements Avoid Freeze/Thaw Cycles
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 20655, 24786

    Superoxide Dismutase 1 Polyclonal Ab PA1-18276 from Thermo Scientific™ detects Superoxide Dismutase 1 in Hu samples, and is validated for IHC (Paraffin, Frozen) and WB

    Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3) (1). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit (2). The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain (3). SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways (4). SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor
    Host Species: Rabbit
    Cross Reactivity: Mouse, Rat
    Isotype: IgG
    Immunogen: Synthetic peptide corresponding to residues A(24) S G E P V V L S G Q I T(36) of mouse superoxide dismutase (SOD1).
    Formulation: 100µL unpurified antibody in whole serum and no preservative
    Synonyms: SOD1, ALS, ALS1, Cu/Zn superoxide dismutase, Homodimer, Indophenoloxidase A, IPOA
    Uniprot Accession: P07632, P08228
    Entrez GeneID: 20655, 24786
    Gene Symbol: SOD1
    PA1-18275 detects Superoxide Dismutase 1 from mouse and rat samples. PA1-18275 has been successfully used in Western blot procedures. The PA1-18275 immunogen is a synthetic peptide corresponding to residues A(24) S G E P V V L S G Q I T(36) of mouse superoxide dismutase (SOD1), conjugated to diphtheria toxoid. Reconstitute with 100 ul of distilled water.

  • Description & Specifications

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit