SFTPD Mouse anti-Human, Clone: 16C11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen HYB2450202
HYB 245-02-02 is specific for human SP-D. HYB 245-02-02 has been successfully used in Immunohistochemistry, ELISA and Western blot procedures. In Western blotting after SDS-PAGE, HYB 245-02 reacts strongly with SP-D, both in reduced and non-reduced forms. HYB 245-02 only reacts with SP-D in the presence of Ca++. The HYB 245-02-02 immunogen is Recombinant neck CRD SP-D. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mLSurfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular ft.head ft. regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins man-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 88 ng/mL in healthy individuals.
|PBS with 15mM sodium azide; pH 7.4|
|Pulmonary surfactant-associated protein D, SP-D, PSP-D, COLEC7, Collectin7, Pulmonary surfactant apoprotein, SFTP4, SFTPD, Surfactant associated prote|
|4° C, store in dark|
|ELISA, Immunohistochemistry (Paraffin), Western Blot|
|Recombit neck CRD SP-D.|
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