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SFTPD Mouse anti-Human, Clone: 16C11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen HYB2450202

Catalog No. HYB2450202


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Description

Description

HYB 245-02-02 is specific for human SP-D.   HYB 245-02-02 has been successfully used in Immunohistochemistry, ELISA and Western blot procedures. In Western blotting after SDS-PAGE, HYB 245-02 reacts strongly with SP-D, both in reduced and non-reduced forms. HYB 245-02 only reacts with SP-D in the presence of Ca++. The HYB 245-02-02 immunogen is Recombinant neck CRD SP-D. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular  ft.head ft. regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins man-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 88 ng/mL in healthy individuals.
Specifications

Specifications

SFTPD
Monoclonal
1.08 mg/mL
PBS with 15mM sodium azide; pH 7.4
P35247
Pulmonary surfactant-associated protein D, SP-D, PSP-D, COLEC7, Collectin7, Pulmonary surfactant apoprotein, SFTP4, SFTPD, Surfactant associated prote
Mouse
IgG1, kappa
200 μL
4° C, store in dark
Primary
6441
ELISA, Immunohistochemistry (Paraffin), Western Blot
16C11
Unconjugated
SFTPD
Liquid
SFTPD
Recombit neck CRD SP-D.
Protein A
RUO
Antibody
Monoclonal
Human
SDS
Documents
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