CD138 Rat anti-Mouse, APC, Clone: 300506, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523553
In direct ELISAs, no cross-reactivity with recombit human Syndecan-1, recombit mouse (rm) Syndecan-3 or rmSyndecan-4 is observed.CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
|Mouse myeloma cell line NS0-derived recombit mouse Syndecan-1/CD138 isoform 1 Gln18-Glu252|
|Buffered saline solution with BSA and 0.09% sodium azide|
|SDC1, SYND1, SDC, CD antigen 138|
|4° C, store in dark, DO NOT FREEZE!|
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