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Syndecan 4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA132485

Catalog No. PA132485


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Description

Description

PA1-32485 detects Syndecan 4 from mouse, rat, human samples. PA1-32485 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue), Western blot, immunoprecipitation applications. Western blot detects a band of approximately 24kDa (predicted molecular weight: 22kDa. The PA1-32485 immunogen is synthetic peptide surrounding amino acid 184 of human Syndecan 4. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.

Syndecans are tyupe I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesencymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
Specifications

Specifications

Syndecan 4
Polyclonal
Unconjugated
SDC4
Liquid
SDC4
Synthetic peptide surrounding amino acid 184 of human Syndecan 4.
Protein A
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.5 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.2
P31431, O35988, P34901
MGC22217, SYND4
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
20971, 24771, 6385
Documents
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