Syndecan 4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA132485

Catalog No. PA132485

Description

PA1-32485 detects Syndecan 4 from mouse, rat, human samples. PA1-32485 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue), Western blot, immunoprecipitation applications. Western blot detects a band of approximately 24kDa (predicted molecular weight: 22kDa. The PA1-32485 immunogen is synthetic peptide surrounding amino acid 184 of human Syndecan 4. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.

Syndecans are tyupe I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesencymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.

Specifications

• Antigen: Syndecan 4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P31431, O35988, P34901
• Gene Symbols: SDC4
• Immunogen: Synthetic peptide surrounding amino acid 184 of human Syndecan 4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.5 mg/mL
• Gene: SDC4
• Gene Alias: MGC22217, SYND4
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20971, 24771, 6385
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid