Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Synphilin 1 Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA118270

Catalog No. 01-670-523


Add to cart

Description

Description

PA1-18270 detects Synphilin-1 from human and rat samples. PA1-18270 has been successfully used in immunohistochemistry and Western blot procedures. The PA1-18270 immunogen is a synthetic peptide corresponding to residues C A S K G K N K A A of human synphilin-1a, conjugated to KLH. After reconstitution keep aliquots at -20°C for a higher stability, and at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. Reconstitute with 100 µL of distilled water. Centrifuge to remove any insoluble material.

Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1.
Specifications

Specifications

Synphilin 1
Polyclonal
whole serum with no preservative
Q9Y6H5
Alpha-synuclein-interacting protein, SNCAIP
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry, Western Blot
Unconjugated
SNCAIP
Lyophilized
SNCAIP
Synthetic peptide corresponding to residues C A S K G K N K A A of human synphilin-1a conjugated to KLH.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
307309, 9627
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit