SYNPO Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521062
A suggested positive control is rat brain tissue lysate. PA5-21062 can be used with blocking peptide PEP-1176.SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|104027, 11346, 60324|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q8N3V7, Q8CC35, Q9Z327|
|A 17 amino acid peptide near the carboxy terminus of human SYNPO.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
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