Syntaxin 1 Rabbit anti-Human, Mouse, Clone: SP36, Invitrogen™

Rabbit Monoclonal Antibody

Supplier:  Thermo Scientific MA516403

Catalog No. PIMA516403

Description

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is cerebral cortex tissue.

Syntaxin 1a is potentially involved in docking of synaptic vesicles at presynaptic active zones and may play a critical role in neurotransmitter exocytosis. Haploinsufficiency of STX1A may be the cause of certain cardiovascular and musculo skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.

Specifications

• Antigen: Syntaxin 1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q16623, O35526
• Gene Symbols: STX1A
• Immunogen: Synthetic peptide derived from N-terminus of human syntaxin 1A
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: SP36
• Gene: STX1A
• Gene Alias: HPC-1, P35-1, STX1, SYN1A, neuron-specific antigen HPC-1, syntaxin-1A
• Host Species: Rabbit
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 20907, 6804
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid