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Syntaxin 6 Mouse, Unlabeled, Clone: 30, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610636

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Catalog No. BDB610636

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Signal transmission between cells is often regulated by the secretion of neurotransmitters or hormones into the extracellular space. This process is controlled by a complex pathway of membrane trafficking which leads to membrane fusion and secretion. Syntaxin 1 is involved in three important complexes that modulate the secretion process: syntaxin and n-sec-1, syntaxin, VAMP, and SNAP-25, and syntaxin, VAMP, SNAP-25, αSNAP, and NSF (20S complex). Syntaxin 6 is a 255 amino acid member of the syntaxin family. It contains a C-terminal transmembrane domain and is located at the Golgi apparatus. In addition, Syntaxin 6 displays significant (47% identity) homology with SNAP-25. In vitro, Syntaxin 6 has been reported to interact with α-SNAP. Syntaxin 6 has been reported to have a calculated molecular weight of 30.6kDa, but has been observed to migrate in a range inbetween ~ 31-35kDa.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting



Syntaxin 6
Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Cell Biology
Canine, Chicken, Frog, Human, Murine, Rat
Western Blot
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Store undiluted at -20°C.
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