MilliporeSigma™ anti-α-Synuclein, Clone: EP1646Y, ™

Supplier:  MilliporeSigma™ 041053/DEL

Catalog No. 50-171-179

Description

α- and β-synuclein are related proteins that have been implicated in the development of Parkinson's disease and the related neurodegenerative condition known as dementia with Lewy bodies. The synucleins (there is a γ isoform as well) are small proteins, less than 140 amino acids, which may function in mictotubule assembly and organization. Synucleins with nitrated tyrosine residues are found in the hallmark lesions of Parkinson's and Lewy Body disease. It has been proposed that the formation of aggregates of nitrated proteins may be at least partly responsible for the cytoxicity of these neurodegenerative diseases.

Host Species: Rabbit
Clone: EP1646Y
Isotype: IgG
Species Reactivity: Human, Rat, Mouse
Epitope: N-terminus
Immunogen: Synthetic peptide corresponding to residues on the N-terminus of human α-synuclein.
Formula Weight [Chemical]: ∽18kDa

Immunocytochemistry, Western Blotting

Specifications

• Antigen: α-Synuclein
• Clone: EP1646Y
• Host Species: Rabbit
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Isotype: IgG

• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Synthetic peptide corresponding to residues on the N-terminus of human α-synuclein.
• Quantity: 100 μL
• Research Discipline: Neuroscience
• Target Species: Human, Mouse, Rat