TADA3L Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527591
PA5-27591 targets TADA3L in WB applications and shows reactivity with Human samples. The PA5-27591 immunogen is recombit fragment corresponding to a region within amino acids 251 and 432 of Human TADA3L. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
|Recombit fragment corresponding to a region within amino acids 251 and 432 of Human TADA3L|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|ADA3, NGG1, TADA3L, hADA3, ADA3 homolog, ADA3-like protein, STAF54, transcriptional adapter 3|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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