TAF13 Mouse anti-Human, Clone: 2B3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA520069
Peptide Sequence: KRKRLFSKEL RCMMYGFGDD QNPYTESVDI LEDLVIEFIT EMTHKAMSIG RQGRVQVEDI VFLIRKDPRK FARVKDLLTM NEELKRARKA FDEANYGSInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6.
|PBS with no preservative; pH 7.4|
|TAF13 RNA polymerase II, MGC22425, TAF2K, TAFII18, TAFII-18, TAF(II)18|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|TAF13 (NP_005636.1, 27 a.a. ∽ 124 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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