TAF2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526964
DescriptionInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators.
|KLH conjugated synthetic peptide between 1152-1180 amino acids from the C-terminal region of human TAF2|
|Antigen Affinity Chromatography, Protein A|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|CIF150, TAF2B, TAFII150, 150 kDa cofactor of initiator function, RNA polymerase II TBP-associated factor subunit B, TAF(II)150, TAFII-150, TATA box binding protein (TBP)-associated factor, RNA polymerase II, B, 150kD, TBP-associated factor 150 kDa, cofactor of initiator function, 150kD|
|-20° C, Avoid Freeze/Thaw Cycles|
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