MilliporeSigma anti-TANK, Polyclonal
Rabbit Polyclonal Antibody
Manufacturer: MilliporeSigma ST1608100UG
Specifically detects TANK Clone: in Human samples, and it is validated for Immuno BlottingThe TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-κB activation. Two transcript variants encoding different isoforms have been found for this gene.
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|Full-length, human TANK (aa 1-119)|
|Immuno Blotting, Immunoblot|
|In PBS, pH 7.2.|
|Recognizes the ∽43-45kDa TANK protein in human liver tissue.|
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