TAOK2 Mouse anti-Human, Clone: 2F4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA520685
Peptide Sequence: ELQCRQYKRK MLLARHSLDQ DLLREDLNKK QTQKDLECAL LLRQHEATRE LELRQLQAVQ RTRAELTRLQ HQTELGNQLE YNKRREQELR QKHAAQVRQQIn vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
|PBS with no preservative; pH 7.4|
|MAP3K17, PSK, PSK1, PSK1-BETA, TAO1, TAO2, PSK-1, hKFC-C, kinase from chicken homolog C, prostate derived STE20-like kinase PSK, prostate-derived STE20-like kinase 1, prostate-derived sterile 20-like kinase 1, serine/threonine-protein kinase TAO2, thousand and one amino acid protein kinase 2|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Proximity Ligation Assay (PLA), Western Blot|
|TAOK2 (AAH51798, 831 a.a. ∽ 930 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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