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TAOK2 Mouse anti-Human, Clone: 2F4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA520685

Catalog No. PIMA520685


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Description

Description

Peptide Sequence: ELQCRQYKRK MLLARHSLDQ DLLREDLNKK QTQKDLECAL LLRQHEATRE LELRQLQAVQ RTRAELTRLQ HQTELGNQLE YNKRREQELR QKHAAQVRQQ

In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
Specifications

Specifications

TAOK2
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9UL54
MAP3K17, PSK, PSK1, PSK1-BETA, TAO1, TAO2, PSK-1, hKFC-C, kinase from chicken homolog C, prostate derived STE20-like kinase PSK, prostate-derived STE20-like kinase 1, prostate-derived sterile 20-like kinase 1, serine/threonine-protein kinase TAO2, thousand and one amino acid protein kinase 2
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
9344
ELISA, Immunocytochemistry, Immunofluorescence, Proximity Ligation Assay (PLA), Western Blot
2F4
Unconjugated
TAOK2
Liquid
TAOK2
TAOK2 (AAH51798, 831 a.a. ∽ 930 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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