TRBP Rabbit anti-Bovine, Human, Mouse, Non-human primate, Rat, Zebrafish, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141109
Suggested positive control: brain lysate.TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
|Synthetic peptide corresponding to residues 150-200 of human TRBP2.|
|Antigen affinity chromatography|
|Bovine, Human, Mouse, Non-human primate, Rat, Zebrafish|
|PBS with 0.05% BSA and 0.05% sodium azide|
|Q0IIG6, Q15633, P97473, Q3SWU0, Q7SXR1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|21357, 336141, 363006, 514674, 6895|
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