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TRBP Rabbit anti-Bovine, Human, Mouse, Non-human primate, Rat, Zebrafish, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141109

Catalog No. PA141109


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Description

Description

Suggested positive control: brain lysate.

TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
Specifications

Specifications

TRBP
Polyclonal
Unconjugated
TARBP2
Liquid
TARBP2
Synthetic peptide corresponding to residues 150-200 of human TRBP2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Human, Mouse, Non-human primate, Rat, Zebrafish
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q0IIG6, Q15633, P97473, Q3SWU0, Q7SXR1
TRBP2
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
21357, 336141, 363006, 514674, 6895
Documents
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