TDP-43 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527221
PA5-27221 targets TARDBP in IF, IHC (P), and WB applications and shows reactivity with Human, mouse, and Rat samples. The PA5-27221 immunogen is recombit protein fragment corresponding to a region within amino acids 178 and 393 of Human TARDBP. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
|Recombit protein fragment corresponding to a region within amino acids 178 and 393 of Human TARDBP|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.01% thimerosal; pH 7|
|ALS10, TDP-43, TAR DNA-binding protein 43, TAR DNA-binding protein-43|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|230908, 23435, 298648|
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