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TBK1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA515053

Catalog No. PIPA515053

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with mouse and Xenopus based on sequence homology.

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.
Specifications

Specifications

TBK1
Polyclonal
PBS with 0.09% sodium azide
Q9UHD2
NAK, Serine/threonine-protein kinase TBK1, TANK-binding kinase 1, T2K, NF-kappa-B-activating kinase, TBK1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
29110
Immunohistochemistry, Western Blot
Unconjugated
TBK1
Liquid
TBK1
KLH conjugated synthetic peptide between 150-181 amino acids from human TBK
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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