TBX19 Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA1803
Tpit (TBX19, T-Box protein 19) is a highly cell-restricted transcription factor belonging to the T-Box family. Tpit is required for pro-opeiomelanocortin (POMC) gene expression and differentiation of corticotroph and melanotroph cells. Tpit gene mutations have been shown to be directly correlated to pituitary adrenocorticotropin (ACTH) deficiencies. Tpit functions as a transcriptional activator by recruiting the p160 family of coactivators.PA1-803 detects endogenous Tpit from mouse AtT-20 cell lysates.PA1-803 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~48kDa protein representing Tpit from AtT-20 cells. PA1-803 immunizing protein, bacterially produced, corresponds to the mouse C-terminal region of Tpit.
|PBS with 0.05% sodium azide|
|TBX19, T-Box protein 19|
|-20° C, Avoid Freeze/Thaw Cycles|
|Mouse recombit protein from C-terminal region Tpit.|
|Ammonium sulfate precipitation|
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