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TC10 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525749

Catalog No. PIPA525749


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Description

Description

This antibody is predicted to react with bovine, chicken, canine, equine, mouse, porcine, non-human primate, rat and yeast based on sequence homology.

TC10 has been classified as a member of the Rho family of GTPases and possesses characteristics most closely related to Cdc42. This family of proteins regulates a wide variety of cellular activity including cytoskeletal rearrangements, motility, proliferation and apoptosis. TC10 is predominately localized to the cell membrane and TC10 mRNA was most highly expressed in heart and skeletal muscle. Recent studies with TC10 mutations have demonstrated that TC10 is responsible for the activation of c-jun amino terminal kinase, the activation of serum response factor-dependent transcription, and the formation of long filopodia. In other studies, TC10 interacts with a similar subset of effectors as Cdc42, but does not react with WASP, MLK3, or ACK-1.
Specifications

Specifications

TC10
Polyclonal
Unconjugated
RHOQ
Liquid
RHOQ
KLH conjugated synthetic peptide between 48-76 amino acids from the central region of human TC10
Protein A, Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.4 mg/mL
PBS with 0.09% sodium azide
P17081
ARHQ, RASL7A, TC10, TC10A, RAS-like, family 7, member A, ras-like protein TC10, ras-like protein family member 7A, rho-related GTP-binding protein RhoQ
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23433
Documents
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