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TCC52 Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA520939

Catalog No. PIPA520939


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Description

Description

A suggested positive control is 293 cell lysate. PA5-20939 can be used with blocking peptide PEP-1053.

Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
Specifications

Specifications

TCC52
Polyclonal
Unconjugated
DCAF12
Liquid
DCAF12
A 15 amino acid peptide near the carboxy terminus of human TCC52.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q5T6F0, Q8BGZ3
CT102, KIAA1892, TCC52, WDR40A; DDB1- and CUL4-associated factor 12; WD repeat domain 40A; WD repeat-containing protein 40A; cancer/testis antigen 102; centrosome-related protein TCC52; testis cancer centrosome-related protein
Chicken
IgY
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
25853, 682812, 68970
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