TCC52 Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA520939
A suggested positive control is 293 cell lysate. PA5-20939 can be used with blocking peptide PEP-1053.Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
|A 15 amino acid peptide near the carboxy terminus of human TCC52.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|CT102, KIAA1892, TCC52, WDR40A; DDB1- and CUL4-associated factor 12; WD repeat domain 40A; WD repeat-containing protein 40A; cancer/testis antigen 102; centrosome-related protein TCC52; testis cancer centrosome-related protein|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|25853, 682812, 68970|
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