TCF12 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521039
A suggested positive control is Hela cell lysate. PA5-21039 can be used with blocking peptide PEP-1153.TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
|A 19 amino acid peptide near the amino terminus of human TCF12.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q99081, Q61286, P51514|
|HEB, HTF4, HsT17266, bHLHb20; DNA-binding protein HTF4; E-box-binding protein; TCF-12; class B basic helix-loop-helix protein 20; helix-loop-helix transcription factor 4; transcription factor HTF-4|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|21406, 25720, 6938|
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