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TCF12 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521039

Catalog No. PIPA521039


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Description

Description

A suggested positive control is Hela cell lysate. PA5-21039 can be used with blocking peptide PEP-1153.

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
Specifications

Specifications

TCF12
Polyclonal
Unconjugated
TCF12
Liquid
TCF12
A 19 amino acid peptide near the amino terminus of human TCF12.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q99081, Q61286, P51514
HEB, HTF4, HsT17266, bHLHb20; DNA-binding protein HTF4; E-box-binding protein; TCF-12; class B basic helix-loop-helix protein 20; helix-loop-helix transcription factor 4; transcription factor HTF-4
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
21406, 25720, 6938
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