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TEK Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514742

Catalog No. PIPA514742


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Description

Description

This antibody is predicted to react with bovine based on sequence homology.

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Specifications

Specifications

TEK
Polyclonal
PBS with 0.09% sodium azide
Q02763
CD202B, TIE-2, TIE2, VMCM, VMCM1, angiopoietin-1 receptor, endothelial tyrosine kinase, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, tunica interna endothelial cell kinase, tyrosine kinase with Ig and EGF homology domains-2, tyrosine-protein kinase receptor TEK, tyrosine-protei
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7010
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
TEK
Liquid
TEK
KLH conjugated synthetic peptide between 758-789 amino acids from the C-terminal region of human TEK (TIE2)
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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