RASD2 Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520439
A suggested positive control is rat colon lysate. PA5-20439 can be used with blocking peptide PEP-0556.Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predomitly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
|A 16 amino acid peptide near the amino terminus of the human TEM2.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|MGC:4834, Rhes, TEM2; GTP-binding protein Rhes; Ras homolog enriched in striatum; tumor endothelial marker 2|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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