transcription factor A, mitochondrial, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human TFAM protein.
Manufacturer: Abnova Corporation H00007019B01P
This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. [provided by RefSeqSequence: MAFLRSMWGVLSALGRSGAELCTGCGSRLRSPFSFVYLPRWFSSVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIKKQRKYGAEEC
|transcription factor A, mitochondrial|
|In 1X PBS, pH 7.4|
|Protein A column|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Mouse polyclonal antibody raised against a full-length human TFAM protein.|
|TFAM (NP_003192.1, 1 a.a. ~ 246 a.a) full-length human protein.|
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