Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

TFII-I/BAP-135 Mouse, Unlabeled, Clone: 42, BD

Mouse Monoclonal Antibody

$207.00

Specifications

Antigen TFII-I/BAP-135
Isotype IgG1
Immunogen Human BAP-135 aa. 17-123
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
View More Specs

Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610942
View Documents
BD Biosciences
610942
50μg Each for $207.00
Add to cart
 
Description

Description

General transcription factor II-I (GTF2I/TFII-I/SPIN/BAP-135) is a transcription factor that contains six directly repeated 90-residue regions, which possess helix-loop-helix protein-protein interaction motifs. TFII-I can regulate transcription in T-cells through interaction with the initiator elments (Inrs) within the AdML and Vβ promoters, and associates with HIV-1, TdT, and ribonucleotide reductase R1 Inrs. In addition, TFII-I associates with the E box motif, the CACGTG sequence, and with serum response element sequences. The helix-loop-helix repeats facilitate TFII-I interaction with other transcription factors, such as USF, Myc, Phox 1, MADS box protein serum response factor, and STATs. TFII-I was also identified as Bruton's tyrosine kinase (btk)-associated protein (BAP-135). TFII-I/BAP-135 is tyrosine phosphorylated by btk and after EGF stimulation, and this phosphorylation enhances TFII-I transcriptional activity. The wide expression of TFII-I and the interaction of TFII-I with various Inrs and transcription factors implicates TFII-I in various signaling pathways that regulate gene transcription.

Immunofluorescence, Western Blotting

Specifications

Specifications

TFII-I/BAP-135
Human BAP-135 aa. 17-123
Unconjugated
Cell Biology
Murine
Affinity Purified
Monoclonal
BAP-135
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
42
250μg/mL
Store undiluted at -20°C.

For Research Use Only.

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit