TGF beta-3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA138736

Catalog No. 01-674-718

Description

This antibody is predicted to react with chicken, canine, mouse, porcine and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta tissue.

Transforming growth factor betas (TGFbetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFbetas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. This antibody does not cross-react with TGFbeta1 or TGFbeta2.

Specifications

• Antigen: TGF beta-3
• Classification: Polyclonal
• Gene: TGFB3
• Gene Alias: TGFb3, ARVD, TGF-beta3, TGF-beta-3, transforming growth factor beta-3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21809, 7043, 25717
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P10600, P17125, Q07258
• Gene Symbols: TGFB3
• Immunogen: Synthetic peptide derived from C-terminus of the precursor form of human TGFbeta3
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rabbit, Rat
• Product Type: Antibody
• Isotype: IgG