TGF beta-1,2,3 Mouse anti-Human, Clone: 1D11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523795
This antibody recognizes human TGF-beta 1, TGF-beta 2, and TGF-beta 3. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.
|PBS with 5% trehalose and No Preservative|
|TGFB, TGFb-1, DPD1, Transforming Growth Factor, Transforming Growth Factor Beta-1, TGF-beta-1, CED|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Inhibition Assays, Neutralization, Western Blot|
|Bovine bone-derived TGF-beta 1 and TGF-beta 2|
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