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TGF beta-1,2,3 Mouse anti-Human, Clone: 1D11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523795

Catalog No. PIMA523795


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Description

Description

This antibody recognizes human TGF-beta 1, TGF-beta 2, and TGF-beta 3. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.
Specifications

Specifications

TGF beta-1,2,3
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P01137
TGFB, TGFb-1, DPD1, Transforming Growth Factor, Transforming Growth Factor Beta-1, TGF-beta-1, CED
Mouse
IgG1
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
7040
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Inhibition Assays, Neutralization, Western Blot
1D11
Unconjugated
TGFB1
Lyophilized
TGFB1
Bovine bone-derived TGF-beta 1 and TGF-beta 2
Protein A/G
RUO
Antibody
Monoclonal
Human
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