TGF beta-3 Mouse anti-Human, Many, Mouse, Clone: 20724, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523812
In Western blots, less than 25% cross-reactivity with Recombinant human (rh) TGF- beta 1.2 and rhTGF-beta 2 is observed, and less than 2% cross-reactivity with Recombinant amphibian TGF-beta 5 and Recombinant human TGF-beta 1 is observed. This antibody neutralizes the biological activity of TGF-beta 3 but not TGF-beta 1, TGF-beta 2, or TGF-beta 5. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.Transforming growth factor betas (TGFbetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFbetas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. This antibody does not cross-react with TGFbeta1 or TGFbeta2.
|PBS with 5% trehalose and No Preservative|
|P10600, P17125, Q07258|
|TGFb3, ARVD, TGF-beta3, TGF-beta-3, transforming growth factor beta-3|
|-20° C, Avoid Freeze/Thaw Cycles|
|21809, 25717, 7043|
|Immunohistochemistry, Neutralization, Western Blot|
|Sf 21-derived recombit human TGF-beta 3 Ala301-Ser412 (Tyr340Phe)|
|Human, Many, Mouse|
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