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TGF beta-3 Mouse anti-Human, Many, Mouse, Clone: 20724, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523812

Catalog No. PIMA523812


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Description

Description

In Western blots, less than 25% cross-reactivity with Recombinant human (rh) TGF- beta 1.2 and rhTGF-beta 2 is observed, and less than 2% cross-reactivity with Recombinant amphibian TGF-beta 5 and Recombinant human TGF-beta 1 is observed. This antibody neutralizes the biological activity of TGF-beta 3 but not TGF-beta 1, TGF-beta 2, or TGF-beta 5. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Transforming growth factor betas (TGFbetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFbetas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. This antibody does not cross-react with TGFbeta1 or TGFbeta2.
Specifications

Specifications

TGF beta-3
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P10600, P17125, Q07258
TGFb3, ARVD, TGF-beta3, TGF-beta-3, transforming growth factor beta-3
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
21809, 25717, 7043
Immunohistochemistry, Neutralization, Western Blot
20724
Unconjugated
TGFB3
Lyophilized
TGFB3
Sf 21-derived recombit human TGF-beta 3 Ala301-Ser412 (Tyr340Phe)
Protein A/G
RUO
Antibody
Monoclonal
Human, Many, Mouse
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