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TGIF Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514151

Catalog No. PIPA514151

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with mouse based on sequence homology.

TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
Specifications

Specifications

TGIF
Polyclonal
PBS with 0.09% sodium azide
Q15583
Homeobox protein TGIF1; 5′-TG-3′-interacting factor 1; TGIF
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7050
Western Blot
Unconjugated
TGIF1
Liquid
TGIF1
KLH conjugated synthetic peptide between 208-237 amino acids from the central region of human TGIF
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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