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PAR1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA138749

Catalog No. 01-674-729


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Description

Description

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is pancreas tissue.

Thrombin is a serine protease that is involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors which include PAR-1, PAR-2 and PAR3.
Specifications

Specifications

PAR1
Polyclonal
PBS with 1% BSA and <0.1% sodium azide; pH 7.6
P25116
CF2R, HTR, PAR-1, PAR1, TR, coagulation factor II receptor, protease-activated receptor 1, proteinase-activated receptor 1, thrombin receptor
Rabbit
IgG
1 mL
4° C, do not freeze
Primary
2149
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
F2R
Liquid
F2R
Synthetic peptide corresponding to near N-terminus of human thrombin R.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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