Thyroglobulin Mouse anti-Human, Clone: TG60, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA110593
MA1-10593 detects Thyroglobulin, specifically both T3 and T4, from human samples. MA1-10593 has been successfully used in ELISA applications. The MA1-10593 immunogen is purified human Thyroglobulin.The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimotoís thyroiditis, Gravesí diseases), with the highest level observed in Hashimotoís thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
|PBS with no preservative; pH 7.4|
|-20° C, Avoid Freeze/Thaw Cycles|
|Purified human Thyroglobulin.|