TIMP1 Mouse anti-Human, Clone: 102D1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MS608PABX
MS608PABX targets TIMP-1 in immunohistochemistry and western blot applications and shows reactivity with human samples. The MS608PABX immunogen is recombit human TIMP-1. MS608PABX detects TIMP-1 which has a predicted molecular weight of approximately 21 kDa.TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
|Recombit human TIMP-1.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with no preservative; pH 7.4|
|TIMP-1; metalloproteinase inhibitor 1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinases 1|