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TIMP1 Mouse anti-Human, Clone: 102D1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MS608PABX

Catalog No. PIMS608PABX


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Description

Description

MS608PABX targets TIMP-1 in immunohistochemistry and western blot applications and shows reactivity with human samples. The MS608PABX immunogen is recombit human TIMP-1. MS608PABX detects TIMP-1 which has a predicted molecular weight of approximately 21 kDa.

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
Specifications

Specifications

TIMP1
Monoclonal
Unconjugated
TIMP1
Liquid
TIMP1
Recombit human TIMP-1.
Protein G
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
102D1
PBS with no preservative; pH 7.4
P01033
TIMP-1; metalloproteinase inhibitor 1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinases 1
Mouse
IgG1
200 μg
-20°C
Primary
7076
Documents
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