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TIMP1 Mouse anti-Human, Clone: 63515, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523756

Catalog No. PIMA523756


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Description

Description

In ELISAs, this antibody does not cross-react with Recombinant mouse (rm) TIMP-1 or rhTIMP-2. Reconstitute at 0.5 mg/mL in sterile PBS.

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
Specifications

Specifications

TIMP1
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P01033
CLGI, EPA, EPO, HCI, TIMP, TIMP-1, collagenase inhibitor, erythroid potentiating activity, erythroid-potentiating activity, fibroblast collagenase inhibitor, metalloproteinase inhibitor 1, tissue inhibitor of metalloproteinases 1
Mouse
IgG2b
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
7076
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
63515
Unconjugated
TIMP1
Lyophilized
TIMP1
Mouse myeloma cell line NS0-derived recombit human TIMP-1 Cys24-Ala207
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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