TIMP1 Mouse anti-Human, Clone: 63515, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523756
In ELISAs, this antibody does not cross-react with Recombinant mouse (rm) TIMP-1 or rhTIMP-2. Reconstitute at 0.5 mg/mL in sterile PBS.TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
|PBS with 5% trehalose and No Preservative|
|CLGI, EPA, EPO, HCI, TIMP, TIMP-1, collagenase inhibitor, erythroid potentiating activity, erythroid-potentiating activity, fibroblast collagenase inhibitor, metalloproteinase inhibitor 1, tissue inhibitor of metalloproteinases 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Mouse myeloma cell line NS0-derived recombit human TIMP-1 Cys24-Ala207|
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