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TIMP1 Mouse anti-Human, Mouse, Rhesus Monkey, Clone: F31 P2 A5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA1773

Catalog No. 01-674-562

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MA1-773 contains 100 µg of in vitro produced, protein A purified antibody (1 mg/mL) in PBS containing 1 mg/mL BSA and 0.05% sodium azide. MA1-773 detects TIMP-1 from human samples. MA1-773 has been successfully used in Western blot, immunofluorescence, and immunohistochemistry procedures. By Western blot, MA1-773 detects a ∽30 kDa band representing TIMP-1 from K562 cell lysate. It is recommended to block with 3% BSA. The MA1-773 immunogen is a synthetic peptide corresponding to residues F(72) Q A L G D A A D I R(82) of mouse TIMP-1.This sequence is 100% conserved in some non-human primate TIMP-1.

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.


1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
P01033, P12032, Q95KL9
TIMP1, Tissue inhibitor of metalloproteinases 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor
100 μg
-20° C, Avoid Freeze/Thaw Cycles
21857, 574348, 7076
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
F31 P2 A5
Synthetic peptide corresponding to residues F(72) Q A L G D A A D I R(82) of mouse TIMP-1.
Protein A
Human, Mouse, Rhesus Monkey
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