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TIMP1 Rabbit anti-Bovine, Equine, Ferret, Human, Ovine, Rabbit, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA185923

Catalog No. PIPA185923


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Description

Description

This antibody does not neutralize the protein activity. Rabbit anti Human TIMP-1 antibody recognizes human Tissue inhibitor of metalloproteinases 1, also known as TIMP-1, Metalloproteinase inhibitor 1, Erythroid-potentiating activity or Fibroblast collagenase inhibitor.

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
Specifications

Specifications

TIMP1
Polyclonal
Unconjugated
TIMP1
Liquid
TIMP1
Human tissue inhibitor of metalloproteinase 1 (TIMP-1).
Purified
RUO
Antibody
Polyclonal
Bovine, Equine, Ferret, Human, Ovine, Rabbit, Rat
ELISA, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P20414, O02722, P01033, P50122, P20614, P30120
RP1-230G1.3, CLGI, EPA, EPO, FLJ90373, HCI, TIMP
Rabbit
IgG
100 μg
4°C or -20°C if preferred
Primary
100009047, 100034220, 116510, 282092, 443331, 7076
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