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TIMP2 Mouse anti-Human, Mouse, Clone: F27 P3 A4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA1774

Catalog No. 01-674-563


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Description

Description

MA1-774 contains 100 µg of in vitro produced, protein A purified antibody (1 mg/mL) in PBS containing 1 mg/mL BSA and 0.05% sodium azide. MA1-774 detects TIMP-2 from mouse samples. MA1-774 has been successfully used in Western blot, IF and immunohistochemistry procedures. By Western blot, MA1-774 detects a ~18-24 kDa band representing TIMP-2 from mouse platelets. It is recommended to block with 3% BSA. The MA1-774 immunogen is a synthetic peptide corresponding to residues D(56) S G N D I Y G N P I(66) of mouse TIMP-2. This sequence is 100% conserved in human, rat, rabbit, chicken, and bovine TIMP-2

Tissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) are inhibitory enzymes of matrix metalloproteinase family. TIMP-1 forms a complex of 1:1 stoichiometry with activated interstitial collagenase, activated stromelysin, active form of 72 kD Type IV collagenase (MMP-2) and latent and active forms 92 kD Type IV collagenase (MMP-9). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Specifications

Specifications

TIMP2
Monoclonal
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
P16035, P25785
TIMP2, Tissue inhibitor of metalloproteinases 2, CSC-21K
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
21858, 7077
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
F27 P3 A4
Unconjugated
TIMP2
Liquid
TIMP2
Synthetic peptide corresponding to residues D(56) S G N D I Y G N P I(66) of mouse TIMP-2.
Protein A
RUO
Antibody
Monoclonal
Human, Mouse
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