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IFRD1 Rabbit anti-Bovine, Canine, Human, Mouse, Non-human primate, Porcine, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523279

Catalog No. PIPA523279


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Description

Description

Tis7, also known as IFRD1, is a 442 amino acid containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family. A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintece, and regeneration in a histone deacetylase dependent manner. 
Specifications

Specifications

IFRD1
Polyclonal
Unconjugated
IFRD1
Liquid
IFRD1
Synthetic peptide (91 TLDKSAKTRQAALEGIKN 108) of Tis7 protein.
Protein A
RUO
Antibody
Polyclonal
Bovine, Canine, Human, Mouse, Non-human primate, Porcine
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
O00458, P19182, Q5S1U6
PC4, TIS7, 12-O-tetradecanoylphorbol-13-acetate-induced sequence 7, TPA induced sequence 7, nerve growth factor-inducible protein PC4, pheochromocytoma cell-4
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
15982, 3475, 482408, 493185, 541283
Documents
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