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CD142 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527278

Catalog No. PIPA527278


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Description

Description

PA5-27278 targets Tissue factor in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27278 immunogen is recombit fragment corresponding to a region within amino acids 10 and 295 of Human Tissue factor. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
Specifications

Specifications

CD142
Polyclonal
Unconjugated
F3
Liquid
F3
Recombit fragment corresponding to a region within amino acids 10 and 295 of Human Tissue factor
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.16 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
P13726
F3, Coagulation factor 3, TF, TFA
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2152
Documents
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