TLR12 Mouse anti-Mouse, Clone: 15F1215, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA141484
Based on sequence homology, this antibody may also detect mouse TLR11.The Toll-like Receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drospphila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney and bladder epithelial cells. TLR12 does not respond to known TLR ligands.
|Synthetic peptide corresponding to residues L-G(791) G L R L C L P E R D F E P G K(806) of mouse TLR12.|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|ascites diluted in PBS with 0.2% gelatin and 0.05% sodium azide|
|Gm287, MGC129352, MGC129353|