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TLR12 Mouse anti-Mouse, Clone: 15F1215, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA141484

Catalog No. 01-676-619


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Description

Description

Based on sequence homology, this antibody may also detect mouse TLR11.

The Toll-like Receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drospphila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney and bladder epithelial cells. TLR12 does not respond to known TLR ligands.
Specifications

Specifications

TLR12
Monoclonal
Unconjugated
Tlr12
Liquid
TLR12
Synthetic peptide corresponding to residues L-G(791) G L R L C L P E R D F E P G K(806) of mouse TLR12.
200 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
384059
Western Blot
15F1215
ascites diluted in PBS with 0.2% gelatin and 0.05% sodium azide
Q6QNU9
Gm287, MGC129352, MGC129353
Mouse
IgM
RUO
Antibody
Monoclonal
Mouse
Documents
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