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TLR4 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526689

Catalog No. PIPA526689


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Description

Description

This antibody is predicted to react with bovine, hamster and porcine based on sequence homology.

TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
Specifications

Specifications

TLR4
Polyclonal
PBS with 0.09% sodium azide
O00206
Toll-like Receptor 4, ARMD10, CD284, TLR-4, TOLL, hToll, homolog of Drosophila toll
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7099
Flow Cytometry, Western Blot
Unconjugated
TLR4
Liquid
TLR4
KLH conjugated synthetic peptide between 669-698 amino acids from the central region of human TLR4
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
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