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TLR5 (CD285) Mouse anti-Human, Alexa Fluor 647, Clone: 624915, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564344

Catalog No. BDB564344

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The 624915 monoclonal antibody specifically binds to TLR5 (Toll-like Receptor 5) which is also known as CD285, MELIOS, SLEB1, and TIL3. TLR5 is a type I transmembrane glycoprotein of the Toll-like Receptor family. It is expressed on mucosal epithelial cells and leucocytes, including monocytes and some immature dendritic cells and CD4-positive T cells. CD285 binds to bacterial flagellin. Flagellin binding induces TLR5 dimerization and intracellular signaling through MyD88 resulting in the cellular production of proinflammatory cytokines and immune system activation.



TLR5 (CD285)
Toll-like receptor 5; MELIOS; SLEB1; TIL3
Affinity Purified
Human TLR5 Recombinant Protein
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
Alexa Fluor 647
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG1, κ
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