TLR5 (CD285) Mouse anti-Human, Alexa Fluor 647, Clone: 624915, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564344
The 624915 monoclonal antibody specifically binds to TLR5 (Toll-like Receptor 5) which is also known as CD285, MELIOS, SLEB1, and TIL3. TLR5 is a type I transmembrane glycoprotein of the Toll-like Receptor family. It is expressed on mucosal epithelial cells and leucocytes, including monocytes and some immature dendritic cells and CD4-positive T cells. CD285 binds to bacterial flagellin. Flagellin binding induces TLR5 dimerization and intracellular signaling through MyD88 resulting in the cellular production of proinflammatory cytokines and immune system activation.
|Toll-like receptor 5; MELIOS; SLEB1; TIL3|
|Human TLR5 Recombinant Protein|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Alexa Fluor 647|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
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