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TLR5 (CD285) Mouse anti-Human, Alexa Fluor 647, Clone: 624915, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564344

Catalog No. BDB564344


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Description

Description

The 624915 monoclonal antibody specifically binds to TLR5 (Toll-like Receptor 5) which is also known as CD285, MELIOS, SLEB1, and TIL3. TLR5 is a type I transmembrane glycoprotein of the Toll-like Receptor family. It is expressed on mucosal epithelial cells and leucocytes, including monocytes and some immature dendritic cells and CD4-positive T cells. CD285 binds to bacterial flagellin. Flagellin binding induces TLR5 dimerization and intracellular signaling through MyD88 resulting in the cellular production of proinflammatory cytokines and immune system activation.

Specifications

Specifications

TLR5 (CD285)
624915
Toll-like receptor 5; MELIOS; SLEB1; TIL3
Affinity Purified
Human TLR5 Recombinant Protein
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
Alexa Fluor 647
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Primary
Human
Documents
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