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TLR7, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523126

Catalog No. PIPA523126

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1) and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1-10) have been described (3). Stimulation of the NFkB signaling pathway by TLR7 suggests that it plays a role in immune response.

Specifications

Specifications

TLR7
Polyclonal
Unconjugated
TLR7
Liquid
TLR7
Synthetic peptide (aa 706-728) of TLR7 protein.
Protein G
RUO
Antibody
Polyclonal
Human, Murine, Rat
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), WB, Western Blot
1.0mg/mL
PBS with 0.05% sodium azide
Q9NYK1, P58681
UNQ248/PRO285
Rabbit
IgG
100μg
Store at -20°C
Primary
170743, 317468, 51284
Documents
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